　

Custom Long Peptide Synthesis

BIO-SYNTHESIS provides custom peptides

and has developed a proprietary synthesis strategy that allows the synthesis of peptides up to about 120

residues - with purity and speed, generally only possible with shorter peptide fragments.

Since most biologically active proteins are about 150 residues in length, however, it has been shown that

most activity is kept within 100 residues. Most commercial proteins are made by recombinant methods,

whereby genes coding for particular peptide sequences are inserted into a host organism,for bulk synthesis.

While the endotoxin contamination can be problematic for recombinant methods, chemical synthesis offers much cleaner products.

BSI has decades of experience in synthesizing >500,000 custom peptides many of them long peptides.

This growing field of long peptide synthesis uses peptide or peptide like compounds for pharmaceutical drug discoveries.

However, the challenge of long peptide synthesis is to overcome the enormous cumulative effect of the yield.

Synthetic inefficiencies associated with peptide aggregation, such as slow or incomplete coupling and/or deprotection reactions,

illustrate the complexity that often arises.

Bio-Synthesis has developed a solid-phase synthesis technology that overcomes these limitations, achieving syntheses of

large proteins entirely by chemical methods. Our team of experts will examine your protein of interest and will assess feasibility

to maximize the success of the synthesis from long and difficult peptides.

　　　　　　　　　　　　　　　　　　　国内実績多数、どうぞ、お問い合せください。

Extra Long Peptide -130 残基

　　直接合成法による製造です。納期、価格は、シーケンス数、合成スケール、精製度、

　　イールド　などを検討の結果、その都度、提示いたします。ご相談ください。

Multi Screening 96 peptides pararel synthesis, 8-20 res

Extra Long Peptide -130 残基

96 peptidesパラレル合成（９６孔マイクロプレート）, 8-20 残基範囲、50-70% purity

0.5-2.0mg 供給/peptide,　MS data 添付

　　\ 580,000 (96peptides)

＜用途＞

Epitope Mapping, Peptide microarray production, Immunogen identification,

Protein to Protein interactions, Receptor-ligand interactions,

Nucleic Acid binding, Screeing application

N-terminus modification, non-standard amino acids available

　　株式会社　バイオロジカ

〒460-0011名古屋市中区大須4-10-40

TEL: 052-262-6732 　　FAX: 052-262-6784
E-MAIL: biologica@biologica.co.jp