RNAの修飾

RNA Modifications
Bio-Synthesis Inc ( Texas )
Bio-Synthesis(BSI) は下記リストにない修飾もチャレンジしますのでお問い合せください。どの修飾を選択すべきかについてもご相談ください。
以下の参考料金表は修飾の追加料金でRNA自体の合成料金は含まれていません。

Internal Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol >5.0 µmol
2,6-Diaminopurine DAP 31,000 31,000 Inquire Inquire
2′-Amino-uridine 2′-N-U 18,000 24,000 37,000 Inquire
2′-Deoxy-uridine dU 2,500 3,700 4,900 Inquire
2′-Fluoro-adenosine 2′-F-A 12,000 25,000 32,000 Inquire
2′-Fluoro-cytidine 2′-F-C 12,000 25,000 32,000 Inquire
2′-Fluoro-acetyl-cytidine 2′-F-Ac-C 12,000 25,000 32,000 Inquire
2′-Fluoro-guanosine 2′-F-G 12,000 25,000 32,000 Inquire
2′-Fluoro-uridine 2′-F-U 12,000 25,000 40,000 Inquire
2-Aminopurine 2AP 22,000 22,000 31,000 Inquire
4-Thio-uridine 4-S-U $250.00 $450.00 Inquire Inquire
5-Bromo-Uridine U[5Br] 12,000 25,000 36,000 Inquire
5-Fluoro-uridine U[5F] 23,000 43,000 43,000 Inquire
5-Iodo-uridine U[5I] 15,000 25,000 31,000 Inquire
5-Methyl-cytidine 5-M-C 7,000 9,000 11,000 Inquire
2′-Amino-cytidine 2′-N-C 19,000 25,000 36,000 Inquire
Inosine I 1,300 1,300 3,100 Inquire
N3-Methyl-uridine 3-M-U 12,000 12,000 31,000 Inquire
Purineribonucleoside Pu 31,000 31,000 Inquire Inquire
Ribo-thymidine rT 12,000 12,000 22,000 Inquire
5-Amino-allyl-uridine N/A 21,000 21,000 31,000 Inquire
Deoxy-abasic N/A 15,000 24,000 31,000 Inquire
N6, N6-Dimethyl-adenosine N/A 15,000 15,000 27,000 Inquire
C3 Spacer SpC3 4,900 6,100 8,600 Inquire
C9 Spacer SpC9 4,900 6,100 8,600 Inquire
C18 Spacer SpC18 6,100 8,600 11,000 Inquire

5’Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol >5.0 µmol
5′-TAMRA-hexyl linker TAM 31,000 31,000 37,000 Inquire
5′-Phosphate 5′-P 4,900 4,900 6,100 Inquire
5′-Amino,(6-carbon)linker N6 5,500 5,500 8,600 Inquire
5′-Amino,(12-carbon)linker N12 9,200 9,200 Inquire Inquire
5’Amino Modified C6 dT N6dT 21,000 21,000 31,000 Inquire
Uni-Link Amino Modifier UniAmM 13,000 13,000 20,000 Inquire
5′-Biotin Bi 8,600 8,600 15,000 Inquire
5′-Photocleavable Biotin 5′-PC-Bi 43,000 43,000 55,000 Inquire
5′-Fluorescein FI 15,000 15,000 27,000 Inquire
5′-Tetrachloro-fluorescein TET 15,000 15,000 27,000 Inquire
5′-Pyrene 5′-Pyr 27,000 27,000 40,000 Inquire
5′-Thiol 5′-Th 21,000 21,000 34,000 Inquire
5′-Dabcyl Dabcyl 21,000 21,000 34,000 Inquire
5′-Cholesterol Chl 24,000 24,000 37,000 Inquire
5′-Cy3TM Cy3 18,000 18,000 24,000 Inquire
C9 Spacer SpC9 4,900 6,100 86,000 Inquire
C18 Spacer SpC18 6,100 7,300 11,000 Inquire

Degenerate Bases
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol >5.0 µmol
Mix site: rA, rG, rC and rU rN 6,100 + 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: rA and rU rW 6,100 + 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: rG and rC rS 6,100+ 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: dA, dG, dC and dT dN 6,100+ 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: dA and dT dW 6,100 + 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: dC and dG dS 6,100+ 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire
Mix site: mA, mG, mC and mU mN 6,100+ 90/site 7,300 + 1,500/site 9,200 + 2,000/site Inquire

3’Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol >5.0 µmol
3′-Biotin 3′-Bi 24,000 24,000 37,000 Inquire
3′-Inverted abasic b 12,000 12,000 21,000 Inquire
3′-Inverted deoxythymidine idT 12,000 12,000 21,000 Inquire
3′-Puromycin Pmn 9,200 9,800 15,000 Inquire
3’Terminal dideoxy-cytidine ddC 13,000 13,000 26,000 Inquire
3′-TAMRA 3′-TAM 34,000 34,000 46,000 Inquire
3′-Fluorescein 3′-Fl 15,000 15,000 27,000 Inquire
3’Terminal deoxy-guanosine 3′-dG 14,000 14,000 26,000 Inquire
3′-Cholesterol 3’Chl 24,000 24,000 37,000 Inquire
3′-Amino Modifier (6 atom) N6-3′ 9,100 9,100 21,000 Inquire

Internal Modifications

5′ Modifications

3′ Modifications

Degenerate Bases