Nucleic Acid Modifications
Bio-Synthesis Inc ( Texas )
Custom Nucleic Acid Synthesis–“FASTEST services in the industry”

Terminus and Internal Modifications

Non-radioactive Labelings

Bases with Altered Paring (以下一部リンク先メーカーサイト)

PCR/Sequencing Utilities (以下一部リンク先メーカーサイト)

Bases Increasing Duplex Stability (メーカーサイト)

  • 2′-5′ Linked Oligonucleotides
  • Constrained Nucleotide
  • 2′-O-methyl Modified Oligonucleotides
  • Methylphosphonate
  • C-Propyne Analogues
  • Morpholino Oligonucleotides
  • C5 – Methyl Analog
  • Chimeric Oligos
  • Phosphorothioate

Photo Cleavable


We offer a personalized solutions to assist client cross link various molecules and compound and solid support attachment. More…

  • Biomolecule-small molecule labelings
  • Biomolecule-biomolecule conjugations
  • Immobilization on solid supports

Antisense Oligonucleotides

Use antisense oligonucleotides for your gene silencing experiments. We hybrid designs using various types of nucleotide analogs to increase high affinity for a successful knockdown experiments. More….

  • Phosphorothioateoligos
  • Constrained ribose (ENA, ZNA)
  • 2′ OMethyl Base
  • 2′ Fluoro RNA
  • Peptide Nucleic Acids (PNA)
  • Peptide Nucleic Acids (PNA)
  • Morpholino
  • 5-Me-dC
  • PropynedC or dU


Fluorophore Labelings (以下リンク先メーカーサイト)

Redox Labels

Bio-Synthesis offers labeling of oligonucleotide or peptide/protein with redox active compounds for electrochemical studies.

  • Dicarboxymethylene Blue
  • Monocarboxymethylene Blue
  • Ferrocene, Ferrocene-C6
  • Anthraquinone, Anthraquinone-C6

Fluorogenic Probes and Primers for Real-time qPCR

  • Labeled Probes
  • Amplifluor Direct® Primers
  • Molecular Beacons for Gene Detection and Analysis
  • Plexor™ Primers
  • Black Hole Scorpion™ Primers

Probes for Multiplexing qPCR

  • Labeled probes
  • Amplifluor® Direct Primer
  • Molecular Beacon
  • Black Hole Scorpions™ Probe, Uni-molecular

Disclaimer: FAMTM, HEXTM, ROXTM, TAMRATM and TETTM are trademarks of Applied Biosystems, Inc. CyTM is a trademark of GE Healthcare; Texas RedTM is a trademark of Molecular Probes Eclipse® and Yakima Yellow® are registered trademarks of Epoch Biosiences, Inc. BHQ 1TM and BHQ 2TM are trademarks of Biosearch Technologies, Inc. BlackBerry (BBQ)TM is a trademark of Berry & Associates, Inc. LightCycler® probes are sold under the license from Roche Diagnostics Gmbh.