オリゴRNA修飾の種類

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RNA Modifications by Bio-Synthesis Inc (Texas)

オリゴRNA合成の修飾

Bio-Synthesis (BSI)社は下記リストにない修飾もチャレンジしますのでお問い合せください。下記リスト以上のスケールやどの修飾を選択すべきかについてもお気軽にご相談ください。
以下の参考料金表は修飾の追加料金でRNA自体の合成料金は含まれていません。

何はともあれまずはお気軽にこちらから見積もりをご用命ください。

RNA合成修飾一覧と参考料金

内部修飾 | 5′ | 縮退 | 3′

Internal Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol
2,6-Diaminopurine DAP 45,000 45,000 見積もり
2′-Amino-uridine 2′-N-U 27,000 36,000 54,000
2′-Deoxy-uridine dU 4,000 5,000 7,000
2′-Fluoro-adenosine 2′-F-A 18,000 36,000 47,000
2′-Fluoro-cytidine 2′-F-C 18,000 36,000 47,000
2′-Fluoro-acetyl-cytidine 2′-F-Ac-C 18,000 36,000 47,000
2′-Fluoro-guanosine 2′-F-G 18,000 36,000 47,000
2′-Fluoro-uridine 2′-F-U 18,000 36,000 60,000
2-Aminopurine 2AP 32,000 32,000 45,000
4-Thio-uridine 4-S-U 45,000 81,000 見積もり
5-Bromo-Uridine U[5Br] 18,000 36,000 54,000
5-Fluoro-uridine U[5F] 34,000 63,000 63,000
5-Iodo-uridine U[5I] 22,000 36,000 45,000
5-Methyl-cytidine 5-M-C 10,000 14,000 16,000
2′-Amino-cytidine 2′-N-C 27,000 36,000 54,000
Inosine I 2,000 2,000 5,000
N3-Methyl-uridine 3-M-U 18,000 18,000 45,000
Purine ribonucleoside Pu 45,000 45,000 見積もり
Ribo-thymidine rT 18,000 18,000 32,000
5-Amino-allyl-uridine N/A 32,000 31,000 45,000
Deoxy-abasic N/A 23,000 36,000 45,000
N6, N6-Dimethyl-adenosine N/A 23,000 23,000 41,000
C3 Spacer SpC3 7,000 9,000 13,000
C9 Spacer SpC9 7,000 9,000 13,000
C18 Spacer SpC18 9,000 11,000 16,000
5’Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol
5′-TAMRA-hexyl linker TAM 45,000 45,000 54,000
5′-Phosphate 5′-P 7,000 7,000 9,000
5′-Amino,(6-carbon)linker N6 8,000 8,000 13,000
5′-Amino,(12-carbon)linker N12 14,000 14,000 見積もり
5’Amino Modified C6 dT N6dT 31,000 31,000 45,000
Uni-Link Amino Modifier UniAmM 19,000 19,000 30,000
5′-Biotin Bi 13,000 13,000 23,000
5′-Photocleavable Biotin 5′-PC-Bi 63,000 63,000 81,000
5′-Fluorescein FI 23,000 23,000 41,000
5′-Tetrachloro-fluorescein TET 23,000 23,000 41,000
5′-Pyrene 5′-Pyr 41,000 41,000 59,000
5′-Thiol 5′-Th 32,000 32,000 50,000
5′-Dabcyl Dabcyl 32,000 32,000 50,000
5′-Cholesterol Chl 36,000 36,000 54,000
5′-Cy3TM Cy3 27,000 27,000 36,000
C9 Spacer SpC9 7,000 9,000 13,000
C18 Spacer SpC18 9,000 11,000 16,000
Degenerate Bases
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol
Mix site: rA, rG, rC and rU rN 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: rA and rU rW 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: rG and rC rS 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: dA, dG, dC and dT dN 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: dA and dT dW 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: dC and dG dS 9,000+1,400/site 11,000+2,300 14,000+3,000
Mix site: mA, mG, mC and mU mN 9,000+1,400/site 11,000+2,300 14,000+3,000
3’Modifications
Synthesis Scales: Mod Code 100 nmole 0.25 µmol 1.0 µmol
3′-Biotin 3′-Bi 36,000 36,000 54,000
3′-Inverted abasic b 17,000 17,000 32,000
3′-Inverted deoxythymidine idT 17,000 17,000 32,000
3′-Puromycin Pmn 14,000 14,000 22,000
3’Terminal dideoxy-cytidine ddC 20,000 20,000 38,000
3′-TAMRA 3′-TAM 50,000 50,000 68,000
3′-Fluorescein 3′-Fl 23,000 23,000 41,000
3’Terminal deoxy-guanosine 3′-dG 20,000 20,000 38,000
3′-Cholesterol 3’Chl 36,000 36,000 54,000
3′-Amino Modifier (6 atom) N6-3′ 14,000 14,000 32,000

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